Background: It has been shown that gut microbiota dysbiosis may induce intestinal permeability, and systemic inflammation, leading to metabolic dysregulation.Furthermore, it has been implicated in the etiology of obesity.Dietary intake is known to affect the gut microbiota.These RCTs suggested that different dietary interventions may exhibit differ
Missense p53 mutations (mutp53) occur in approx.70% of pancreatic ductal adenocarcinomas (PDAC).Typically, mutp53 proteins are aberrantly stabilized by Hsp90/Hsp70/Hsp40 chaperone complexes.Notably, stabilization is a precondition for specific abc material mutp53 alleles to acquire powerful neomorphic oncogenic gain-of-functions (GOFs) that promote
Agro-industrial residues have attracted attention for their applications in the field of biodegradable packaging.Recently, our research group has developed onion-based films with promising properties for this type of application due to their non-toxicity, biocompatibility and biodegradability.Therefore, in this study, we investigated the effect of
Background: Epidermoid cysts (ECs) are rare, benign lesions which comprise less than 1 % of all spinal tumors.Calcification of spinal ECs is rare, and EC ossification within the lumbar spine has never been documented.We report the only known congenital lumbar epidermoid tumor with ossification and a literature review of intradural lumbar ECs.Method
Abstract Small intestinal neuroendocrine tumors (siNETs) are rare bowel tumors arising from malignant enteroendocrine cells, which normally regulate digestion throughout the intestine.Though infrequent, their incidence is rising through better diagnosis, fostering research into their origin and treatment.To date, siNETs are considered to be a singl